Hexahydro-3a,7a-dimethyl-4,7-epoxyisobenzofuran-1,3-dione White solid. Inhibitor of protein phosphatase 2A (IC50 = 40 nM). Inhibits protein phosphatase 1 at higher concentrations (IC50 = 473 nM). Purity: ≥98% by TLC. RTECS RN8575000, CAS 56-25-7. Merck Index: 14, 1752
Ref.: Li, Y.-M., et al. 1993. Biochem. Pharmacol. 46, 1435. Li, Y.-M., and Casida, J.E. 1992. Proc. Natl. Acad. Sci. USA 89, 11867. Graziano, M.J., et al. 1988. Mol. Pharmacol. 33, 706.
R: 28-36/37/38; S: 45-53 |
