Carbamoylcholine Chloride

White fine crystalline solid. HYGROSCOPIC. An unsubstituted carbamoyl ester that acts as an agonist for nicotinic and muscarinic acetylcholine receptors. Carbachol is totally resistant to the action of acetylcholine esterase (AChE) and non-specific cholinesterases. Inhibits apoptotic death of cultured granule neurons. Purity: ≥99% by titration. RTECS GA0875000, CAS 51-83-2.

Merck Index: 14, 1779
Ref.: Jence, M., et al. 1995. J. Neurochem. 64, 1605. Yan, G.M., et al. 1995. Mol. Pharmacol. 47, 248. Mangels, L.A., and Gnegy, M.E. 1992. J. Biol. Chem. 267, 5847. Watanabe, A.M., et al. 1992. In Basic and Clinical Pharmacology, Fifth Edition Katzung, B.G. ed.) Appleton and Lange, Norwalk, CT, p. 82. Howe, P.H., et al. 1986. J. Pharmacol. Exp. Ther. 239, 574.
R: 26/27/28-36/37/38; S: 22-36/37/39-45