CCCP Yellow solid. Protonophore. Uncoupling agent for oxidative phosphorylation that inhibits mitochondrial function. Approximately 100 times more effective than 2,4-dinitrophenol. Binds with cytochrome c oxidase with high affinity (Kd = 270 nM). Inhibits transport processes and depresses growth. Purity: ≥95% by HPLC. RTECS FG5600000, CAS 555-60-2. Ref.: Bona, M., et al. 1993. Gen. Physiol. Biophys. 12, 533. Heytler, P.G., and Prichard, W.W. 1962. Biochem. Biophys. Res. Commun. 7, 272.
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