Off-white solid. HYGROSCOPIC. Toxic compound originally isolated from the Mediterranean thistle Atractylis gummifera. A highly selective inhibitor of the cytosolic side-specific mitochondrial ADP/ATP carrier (AAC; Ki <10 nM). Purity: ≥95% by TLC. RTECS NZ8173500, CAS 35988-42-2. Ref.: Huber, T., et al. 1999. Biochemistry 38, 762. Streicher-Scott, J., et al. 1993. Anal. Biochem. 210, 69. Vignais, P.M., et al. 1979. Methods Enzymol. 55, 518.
R: 23/24/25; S: 36/37/39-45 |
