Anti-b2 Integrin

Host: Mouse

Isotype: IgG2a

Immunogen: human peripheral blood monocytes

Form: Liquid

Formulation: In 150 mM NaCl, 100 mM KCl, 50 mM sodium phosphate, pH 7.5.

Preservative: 0.05 mg/ml gentamicin sulfate

Purity: ≥95% by SDS-PAGE

Positive Control: HPB-MLT cells

Negative Control: Nalm-6 cells

Comments: Recognizes the ~95 kDa b2 integrin subunit. Blocks the binding of ICAM-1 and ICAM-3 to LFA-1.

Ref.: Berman, M.E., et al. 1996. J. Immunol. 156, 1515. Kaneko, M., et al. 1995. J. Immunol. 155, 2631. Mazzone, A., and Ricevuti, G. 1995. Haematologica 80, 161. Kaneko, M., et al. 1995. J. Immunol. 155, 2631. Landis, R.C., et al. 1994. J. Cell Biol. 126, 529. Wright, S.D., et al. 1983. Proc. Natl. Acad. Sci. USA 80, 5699.