Ac-VAD-AFC Lyophilized. PROTECT FROM LIGHT. Fluorogenic caspase-1 substrate. May also be used as a caspase-3, caspase-4, or caspase-7 substrate. Reaction can be monitored by a blue to green shift in fluorescence upon cleavage of the AFC fluorophore. Purity: ≥95% by HPLC. Excitation max.: 400 nm, Emission max.: 505 nm Ac-VAD-AFC Ref.: Susin, S.A., et al. 1999. J. Exp. Med. 189, 381. Thornberry, N.A. and Lazebnik, Y. 1998. Science 281, 1312. |
