Ac-VDVAD-CHO Off-white lyophilized solid. PACKAGED UNDER INERT GAS. A potent, reversible inhibitor of caspase-2 (Ki = 3.5 nM), caspase-3 (Ki = 1 nM) and caspase-7 (Ki = 7.5 nM). Also serves as an inhibitor of DRONC (Drosophila caspase), a glutamate/aspartate protease. Purity: ≥95% by HPLC. Ac-Val-Asp-Val-Ala-Asp-CHO Ref.: Dorstyn, L., et al. 1999. Proc. Natl. Acad. Sci. USA 96, 4307. Talanian, R.V., et al. 1997. J. Biol. Chem. 272, 9677. |
