Z-VDVAD-AFC Lyophilized. PROTECT FROM LIGHT. PROTECT FROM MOISTURE. A fluorogenic substrate for the detection of caspase-2 (ICH-1). Reaction can be monitored visually or quantitatively by a blue to green shift in fluorescence upon cleavage of the AFC fluorophore. Purity: ≥95% by HPLC. Excitation max.: ~400 nm, Emission max.: ~505 nm Z-Val-Asp-Val-Ala-Asp-AFC Ref.: Ito, A., et al. 1999. Biochim. Biophys. Acta 1452, 263. Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312. Talanian, R.V., et al. 1997. J. Biol. Chem. 272, 9677. |
