Calbiochem: 218750: Caspase-3 Inhibitor III

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��	Caspase-3 Inhibitor III

Cat. No. 218750��

All Categories � Calbiochem � Inhibitors � Apoptosis � Caspase

Ac-DEVD-CMK

Off-white to brown solid. PROTECT FROM MOISTURE. A potent, cell-permeable, and irreversible inhibitor of caspase-3 as well as caspase-6, caspase-7, caspase-8, and caspase-10. Purity: ≥98% by HPLC.

Ac-Asp-Glu-Val-Asp-CMK

Ref.: Mocanu, M.M., et al. 2000. Br. J. Pharmacol. 130, 197 Schrantz, N., et al. 1999. Cell Death Differ. 6, 445. Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.

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Solubility	Molecular Formula	Mol. Wt.
DMSO�	C₂₁H₃₁ClN₄O₁₁�	551.0�

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218750: Caspase-3 Inhibitor III - English
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Related Categories:
All Categories � Calbiochem � Inhibitors � Apoptosis � Caspase

Selected Citations:
Yumin Zhang, et al. (2004) Peroxynitrite-Induced Neuronal Apoptosis is Mediated by Intracellular Zinc Release and 12-Lipoxygenase Activation. Journal of Neuroscience 24, 10616-10627.

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