MCA-VDQMDGWK(DNP)-NH2 Yellow lyophilized solid. PROTECT FROM LIGHT. PROTECT FROM MOISTURE. A fluorogenic resonance energy transfer substrate for the detection of caspase-3 (Apopain, CPP32, Yama) activity. Purity: ≥95% by HPLC. Excitation max.: ~325 nm, Emission max.: ~392 nm MCA-Val-Asp-Gln-Met-Asp-Gly-Trp-Lys-(DNP)-NH2 Ref.: Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312. Talanian, R.V., et al. 1997. J. Biol. Chem. 272, 9677. Enari, M., et al. 1996. Nature 380, 723. |
