Liquid. Each inhibitor supplied at 1 mM in DMSO. PROTECT FROM LIGHT. Ready-to-use substrates for assaying the activity of various members of the caspase-family proteases. Contains 125 µl (1 mM) each of Caspase-1 Substrate VI, Ac-YVAD-AFC (Cat. No. 688224); Caspase-2 Substrate I, Ac-VDVAD-AFC (Cat. No. 218740); Caspase-3 Substrate IV, Ac-DEVD-AFC (Cat. No. 264150); Caspase-5 Substrate II, Ac-WEHD-AFC (Cat. No. 218754); Caspase-6 Substrate III, Ac-VEID-AFC (Cat. No. 218763); Caspase-8 Substrate I, Z-IETD-AFC (Granzyme B Substrate II, Cat. No. 368059); and Caspase-9 Substrate I, Ac-LEHD-AFC (Cat. No. 218765). Supplied with a data sheet.

Ref.: Humke, E.W., et al. 1998. J. Biol. Chem. 273, 15702. Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312. Takahashi, A., et al. 1997. Exp. Cell Res. 231, 123. Thornberry, N.A., et al. 1997. J. Biol. Chem. 272, 17907. Nicholson, D.W., et al. 1995. Nature 376, 37. Thornberry, N.A., et al. 1992. Nature 356, 768. Zimmerman, M., et al. 1977. Anal. Biochem. 78, 47.
R: 36/38; S: 26