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  Caspase Inhibitor VI
Cat. No. 219007  
All Categories » Calbiochem » Inhibitors » Apoptosis » Caspase

Z-VAD-FMK

Off-white solid. PROTECT FROM MOISTURE. An irreversible general caspase inhibitor. Useful for studies involving recombinant, isolated, and purified caspase enzymes. Unlike Caspase Inhibitor I (Cat. No. 627610), this inhibitor does not require pretreatment with esterase for in vitro studies. Purity: ≥95% by TLC.

Z-Val-Ala-Asp-CH2F*

Ref.: Misaghi, S., et al. 2004. Chem. Biol. 11, 1677.

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EMD Chemicals Inc. USD list price is displayed (pricing with local distributors may vary). NOTE: In Stock status is based on item availability worldwide.

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250 µgY$71.00
1 mgY$196.00


SolubilityMolecular FormulaMol. Wt.
DMSO C21H28FN3O7 453.5 


Related Literature:

Caspases and other Apoptosis Related Tools Brochure
Inhibitor Sourcebook
Tools and Tips for Analyzing Apoptosis

Material Safety Data Sheets:
219007: Caspase Inhibitor VI - English
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Related Categories:
All Categories » Calbiochem » Inhibitors » Apoptosis » Caspase

Selected Citations:
  1. Liwei Chen, et al. (2005) Chemical ablation of androgen receptor in prostate cancer cells by the histone deacetylase inhibitor LAQ824. Molecular Cancer Therapeutics 4, 1311-1319.
  2. Heui-Young Ryu, et al. (2005) Environmental Chemical-Induced Bone Marrow B Cell Apoptosis: Death Receptor-Independent Activation of a Caspase-3 to Caspase-8 Pathway. Molecular Pharmacology 68, 1087-1096.
  3. Yumin Zhang, et al. (2004) Peroxynitrite-Induced Neuronal Apoptosis is Mediated by Intracellular Zinc Release and 12-Lipoxygenase Activation. Journal of Neuroscience 24, 10616-10627.
  4. Dong Zhang, et al. (2001) Granzymes A and B Directly Cleave Lamins and Disrupt the Nuclear Lamina During Granule-Mediated Cytolysis. Proceedings of the National Academy of Science USA 98, 5746-5751.
  5. Brian L. Webb, Elsa Jimenez and G. Steven Martin. (2000) v-Src Generates a p53-Independent Apoptotic Signal. Molecular and Cellular Biology 20, 9271-9280.
 
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