White solid. PROTECT FROM LIGHT. PACKAGED UNDER INERT GAS. A potent, selective, reversible, competitive, non-peptide inhibitor of cathepsin G [IC50 = 53 nM and Ki = 63 nM]. Weakly inhibits chymotrypsin (Ki = 1.5 µM) and poorly inhibits thrombin, factor Xa, factor IXa, plasmin, trypsin, tryptase, proteinase 3, and human leukocyte elastase (IC50 > 100 µM). Purity: ≥98% by HPLC. Ref.: Greco, M.N., et al. 2002. J. Am. Chem. Soc. 124, 3810. |
