(Z-LR)2-Rh 110 Yellow lyophilized solid. Supplied as a trifluoroacetate salt. PROTECT FROM LIGHT. PROTECT FROM MOISTURE. PACKAGED UNDER INERT GAS. A cell-permeable peptidyl (Leu-Arg)-Rhodamine 110-bisamide that acts as a highly sensitive, selective, and photostable fluorogenic substrate for cathepsin K. Has been used to analyze cathepsin K activity using either extract or intact cell preparations of CHO cells. Purity: ≥95% by HPLC. Excitation max.: ~485 nm, Emission max.: ~535 nm (Z-Leu-Arg)2-Rhodamine 110 Ref.: Claveau, D., et al. 2000. Biochem. Pharmacol. 60, 759. Guay, J., et al. 1999. Bone 25, 205. |
