Bz-RGFFP-4-MeObNA, HCl

White lyophilized solid. PROTECT FROM LIGHT. PROTECT FROM MOISTURE. Useful as a substrate for the determination of cathepsin D activity. Suitable for either colorimetric or fluorometric assay. Cathepsin D hydrolyzes the Phe-Phe bond. Requires dipeptidyl aminopeptidase II to free 4-methoxy-b-naphthylamine (4MeObNA). Purity: ≥95% by HPLC. Excitation max.: ~345 nm, Emission max.: ~425 nm

Bz-Arg-Gly-Phe-Phe-Pro-4MeObNA, HCl

Ref.: Takahashi, T., and Tang, J. 1981. Methods Enzymol. 80, 565. Smith, R.E., and Van Frank, R.M. 1975. in Lysosomes in Biology and Pathology 4 (Dingle, J.T., and Dean, R.T., eds.) p. 193, American Elsevier, Holland.