Liquid. In 100 mM NaCl, 20 mM sodium acetate buffer, 1 mM EDTA, pH 4.5. AVOID FREEZE/THAW CYCLES. Native cathepsin H from human liver. Functions both as an aminopeptidase and as an endopeptidase. Involved in catabolism of proteins in the lysosomal system. Specific activity: ≥200 mU/mg protein. One unit is defined as the amount of enzyme that will hydrolyze 1.0 µmol H-Arg-bNA per min at 40°C, pH 6.8. Prepared from tissue of individuals that have been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV. EC 3.4.22.6, CAS 60748-73-4. Note: 1 mU = 1 milliunit. Merck Index: 14, 1905 Ref.: Kurata, M., et al. 2001. J. Biochem. (Tokyo). 130, 857. Taniguchi, K., et al. 1993. Brain Res. 601, 143. Erickson, A. 1989. J. Cell. Biochem. 40, 31. Schwartz, W.N., and Barrett, A.J. 1980. Biochem. J. 191, 487. |