Z-FG-NHO-BzOME

White solid. PROTECT FROM LIGHT. PROTECT FROM MOISTURE. Cysteine protease inhibitor. Selectively inhibits cathepsin B (k₂/K_i = 1 x 10⁴ M^-1 sec^-1), cathepsin L (k₂/K_i = 1.5 x 10⁵ M^-1 sec^-1), cathepsin S (k₂/K_i = 6.6 x 10⁴ M^-1 sec^-1), and papain (k₂/K_i = 1 x 10³ M^-1 sec^-1). Purity: >90% by HPLC. Half-life in buffered solution (pH 5-9) = 37 h (30°C); 300 h (0°C).

Z-Phe-Gly-NHO-Bz-pOMe

Ref.: Demuth, H.-U., et al. 1996. Biochim. Biophys. Acta 1295, 179. Brömme, D., and Demuth, H.-U. 1994. Methods Enzymol. 244, 671.