| Host: Rabbit | | Isotype: IgG | | Immunogen: a synthetic phosphopeptide corresponding to amino acids surrounding the Tyr15 phosphorylation site of human Cdk1 | | Form: Liquid | | Formulation: In 150 mM NaCl, 10 mM sodium HEPES, 100 mg/ml BSA, 50% glycerol, pH 7.5. | | Preservative: None | | Comments: Recognizes the ~34 kDa Cdk1 protein, phosphorylated at Tyr15, in hydroxyurea treated SaoS cell extracts. Also recognizes phosphorylated Cdk2. Does not react with Cdk4, Cdk6, Cdk7, or other phosphotyrosine proteins. | | Ref.: Norbury, C., and Nurse, P. 1992. Annu. Rev. Biochem. 61, 441. Hunter, T. 1995. Cell 80, 225. Galaktionov, K., et al. 1995. Genes Dev. 9, 1046. Watanabe, K., et al. 1995. EMBO J. 14, 1878. Atherton-Fessler, S., et al. 1993. Mol. Cell. Biol. 13, 1675. McGwan, C.H. and Russel, P. 1993. EMBO J. 12, 75. |
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