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Inhibitor Resource
  Cdk Inhibitor, p35
Cat. No. 219457  
All Categories » Calbiochem » Inhibitors » Kinase and Phosphatase » Cyclin-Dependent Kinase (Cdk)

2-(3-Hydroxypropylamino)-6-(o-hydroxybenzylamino)-9-isopropylpurine

Yellow solid. PROTECT FROM LIGHT. PACKAGED UNDER INERT GAS. An analog of Olomoucine (Cat. No. 495620) that acts as a potent inhibitor of Cdk1 (IC50 = 100 nM) and Cdk2 (IC50 = 80 nM). Also displays anti-proliferative and pro-apoptotic effects. The correlation between inhibition of Cdk1/Cdk2 and inhibition of cell proliferation suggests that the anti-proliferative effects are due, in part, to Cdk inhibition. Purity: ≥95% by HPLC.

Ref.: Vermeulen, K., et al. 2002. Leukemia 16, 299.

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1 mgY$80.00


SolubilityMolecular FormulaMol. Wt.
DMSO C18H24N6O2 356.4 


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219457: Cdk Inhibitor, p35 - English
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Related Categories:
All Categories » Calbiochem » Inhibitors » Kinase and Phosphatase » Cyclin-Dependent Kinase (Cdk)