C8 Ceramide White solid. A short chain cell-permeable analog of endogenous ceramide. Shown to induce apoptosis in a variety of cell lines and to activate MAP kinase in HL-60 cells. Purity: ≥98% by TLC. Ref.: Hannun, Y.A. 1994. J. Biol. Chem. 269, 3125. Jarvis, W.D., et al. 1994. Proc. Natl. Acad. Sci. USA 91, 73. Raines, M.A., et al. 1993. J. Biol. Chem. 268, 14572. Mathias, S., et al. 1991. Proc. Natl. Acad. Sci. USA 88, 10009. R: 36/37/38; S: 26-36 |