3-[(3-Cholamidopropyl)dimethylammonio]-2-hydroxy-1-propanesulfonate White solid. Unique detergent with high CMC that solubilizes membrane-bound proteins in their native state. Capable of solubilizing opiate receptor to a state exhibiting reversible binding of opiates. Has higher solubility than CHAPS because of its more polar head group. Aggregation number: 11. Purity: >98% by TLC. Aggregation number 11, CMC 8 mM, micellar weight 9960. CAS 82473-24-3. Ref.: Simonds, W.F., et al. 1980. Proc. Natl. Acad. Sci. USA 77, 4623. |