White solid. HYGROSCOPIC. Highly purified and intended for use as a detergent to solubilize membrane-bound proteins in their native state. Reported to induce tyrosine phosphorylation of b-catenin and its subsequent translocation to the nucleus, promoting activation of b-catenin signaling (effective concentration 5-50 µM). Aggregation number: 3-12. Purity: ≥99% by TLC. Absorbance (10%, H2O, 290 nm):≤0.25. Aggregation number 3 - 12, CMC 2 - 6 mM, micellar weight 1200 - 4900. pKa 6.2. RTECS FZ2250000, CAS 302-95-4. Merck Index: 14, 2899
Ref.: Pai, R., et al. Mol. Biol. Cell 15, 2156.
R: 22; |
