CD26
DPPIV Liquid. In 20 mM Tris-HCl, 5 mM CaCl2, 1 µM ZnCl2, 0.05% NaN3, pH 8.0. AVOID FREEZE/THAW CYCLES. Recombinant, human DPP IV expressed in S. frugiperda insect cells. A serine exopeptidase dimer composed of two identical subunits of 110-130 kDa. DPPIV is involved in many cellular processes such as activation of cytokines, differentiation, and cell-matrix interactions. Inhibition of DPPIV has been reported to be an effective treatment for type II diabetes. Note: 1 mU = 1 milliunit. Specific activity: ≥8 U/mg protein. One unit is defined as the amount of enzyme that will hydrolyze 1 µmole H-Gly-Pro-AMC per min at 37°C, pH 8.0. Purity: ≥90% by SDS-PAGE. EC 3.4.14.5. Note: 1 mU = 1 milliunit. Ref.: Pospisilik, JA, et al. 2003. Diabetes 52, 741. Dobers, J., et al. 2002. Protein Expr. Purif. 25, 527. Marguet, D., et al. 2000. Proc. Natl. Acad. Sci. 97, 6874. Misumi, Y., et al. 1992. Biochim. Biophys. Acta 1131, 333. |
