2-Phenyl-1,2-benzisoselenazol-3(2H)-one
PZ51

Lyophilized solid. A cell-permeable, non-selective inhibitor of COX-1 and COX-2. An excellent scavenger of peroxynitrite. Glutathione peroxidase mimetic. Inhibits radiation-induced apoptosis in thymocytes by scavenging peroxides. A neuroprotective agent active against acute focal ischemic injury. Inhibits LPS-induced NF-kB nuclear translocation and LPS-induced phosphorylation of JNK. Purity: ≥98% by TLC. CAS 60940-34-3.

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