PMN Elastase Lyophilized solid. Salt-free. Native elastase from human neutrophil. A serine protease that degrades elastin, collagen, and proteoglycans. Its overexpression has been implicated in the development of pulmonary emphysema, rheumatoid arthritis, and cystic fibrosis. Specific activity: ≥20 units/mg protein.. One unit is defined as the amount of enzyme that will hydrolyze 1.0 µmol of MeO-Suc-Ala-Ala-Pro-Val-pNA (Cat. No. 454454) per min at 25°C, pH 8.0. Purity: Major band by SDS-PAGE. Prepared from blood that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV. EC 3.4.21.37, RTECS JX7069000, CAS 9004-06-2. Merck Index: 14, 3535
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