EPO Erythropoietin-a Liquid. In 300 mM NaCl, 20 mM Na/K phosphate, pH 7.5. Recombinant, human erythropoietin (EPO) expressed in CHO cells. EPO is a glycoprotein produced by the kidneys and is involved in red blood cell production. It has a predicted molecular mass of ~21 kDa but migrates at ~37 kDa on SDS-PAGE. Specific activity: ≥1.0 X 105 IU/mg protein. Purity: ≥98% by HPLC. Contaminants: Endotoxin: <10 EU/10 µg protein. Sialic acid content: > 10 moles/mole of protein. RTECS KF5885000, CAS 11096-26-7. Merck Index: 14, 3688 Ref.: Frank, S.J. 2002. Endocrinology 143, 2. Cerami, A. 2001. Semin. Hematol. 38, 33. Donnelly, S. 2001. Am. J. Kidney Dis. 38, 415. Goodnough, L.T. 2001. Curr. Opin. Hematol. 8, 405. Jelkmann, W, and Hellwig-Burgel, T. 2001. Adv. Exp. Med. Biol. 502, 169. Siren, A.L., and Ehrenreich, H. 2001. Eur. Arch. Psychiatry Clin. Neurosci 251, 179. Hansson, G.K., et al. 1992. Scand. J. Clin. Lab. Invest. 52, 35. Lee, L.G., et al. 1986. Cytometry 7, 35. |