EDCI
1-Ethyl-3-(3′-dimethylaminopropyl)carbodiimide, HCl

White solid. PROTECT FROM MOISTURE. HYGROSCOPIC. Water-soluble carbodiimide derivative. Used to modify NMDA receptors. Also useful for conjugating haptens to proteins or polypeptides. Molar absorptivity (~212 nm; 50 mM phosphate buffer, pH 8):≥6800 M^-1cm^-1. RTECS FF2200000, CAS 25952-53-8.

Ref.: Chazot, P.L., et al. 1993. Biochem. Pharmacol. 45, 605. Richardson, A., et al. 1992. Biochem. Pharmacol. 43, 1415. Taniuchi, M., et al. 1986. Proc. Natl. Acad. Sci. USA 83, 1950. Chase, J.W., et al. 1983. Proc. Natl. Acad. Sci. USA 80, 5480. Williams, A., et al. 1981. J. Am. Chem. Soc. 103, 7090. Yamada, H., et al. 1981. Biochemistry 20, 4836. Thomas, J.O., et al. 1978. J. Mol. Biol. 123, 149. Ozawa, H. 1970. Biochemistry 9, 2158. Kopple, K.D., et al. 1962. J. Am. Chem. Soc. 84, 4457.