5,10,15,20-Tetrakis(4-sulfonatophenyl)porphyrinato Iron (III), Chloride Dark brown solid. PROTECT FROM LIGHT. HYGROSCOPIC. PACKAGED UNDER INERT GAS. A ferric porphyrin complex that catalytically isomerizes peroxynitrite to nitrate both in vivo and in vitro. Hence, serves as a selective peroxynitrite scavenger and decomposition catalyst. Provides cytoprotection against peroxynitrite (EC50 = 5 µM). Does not complex with nitric oxide and exhibits minimal SOD mimetic activity. Purity: ≥95% by TLC. Ref.: Imam, S.Z., et al. 2000. Ann. N.Y. Acad. Sci. 914, 157. Misko, T.P., et al. 1998. J. Biol. Chem. 273, 15646. |
