Lyophilized. Lyophilized solid from a 0.2 µm filtered solution in 30% acetonitrile, 0.1% TFA, 50 µg BSA/µg cytokine. Recombinant, rat fractalkine (amino acids 25 - 100) expressed in E. coli. A member of the delta chemokine family that contains a novel CX3-C motif. Biological activity: ED50 = 3-9 ng/ml based on the ability to induce chemotaxis of human peripheral blood lymphocytes. Purity: ≥97% by SDS-PAGE. Contaminants: endotoxin: <1.0 EU/µg cytokine. Ref.: Goda, S., et al. 2000. J. Immunol. 164, 4313. Zujovic, V., et al. 2000. Glia 29, 305. Combadiere, C., et al. 1998. J. Biol. Chem. 273, 23799. Harrison, J.K., et al. 1998. Proc. Natl. Acad. Sci. USA 95, 10896. Rossi, D.L., et al. 1998. Genomics 47, 163. Bazan, J.F., et al. 1997. Nature 385, 640. |
