FB1 White powder. A cell-permeable mycotoxin that inhibits sphingolipid biosynthesis in rat kidney and in liver microsomes by inhibition of sphingosine N-acyltransferase (ceramide synthase; IC50 = 100 nM). Preferentially inhibits sphingomyelin biosynthesis in neuronal cells. Exhibits carcinogenic properties. Purity: ≥95% by TLC. RTECS TZ8350000, CAS 116355-83-0. Merck Index: 14, 4289
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R: 40; S: 22-26-36/37/39 |
