g-GCE
L-g-Glutamyl-L-cysteinyl Ethyl Glycinate
GSH-MEE

White solid. HYGROSCOPIC. PACKAGED UNDER INERT GAS. Cell-permeable derivative of glutathione (GSH) that undergoes hydrolysis by intracellular esterases to release GSH. Effective transport of GSH-MEE has been used to protect cells against damage from radiation, oxidants, and various toxic compounds including heavy metals. A protective agent against cellular damage such as in cataracts and mitochondrial degeneration. Purity: >90% by TLC. CAS 118421-50-4.

Ref.: Grattagliano, I., et al. 1995. J. Pharmacol. Exp. Ther. 272, 484. Martensson, J., et al. 1993. Proc. Natl. Acad. Sci. USA 90, 317. Anderson, M.E., and Meister, A. 1989. Anal. Biochem. 183, 16. Anderson, M.E., et al. 1985. Arch. Biochem. Biophys. 239, 538. Wellner, V.P., et al. 1984. Proc. Natl. Acad. Sci. USA 81, 4732. Puri, R.N., and Meister, A. 1983. Proc. Natl. Acad. Sci. USA 80, 5258.