GPHRSTPESRAAV White solid. Supplied as a trifluoroacetate salt. HYGROSCOPIC. PACKAGED UNDER INERT GAS. A part of the hydrophilic loop domain of presenilin 1 that is selectively recognized by GSK-3b. The sequence is not recognized by p38a, p38b, PKC, or Casein Kinase II. Undergoes phosphorylation at the Ser353 and Ser357 sites. Purity: ≥95% by HPLC.. H-Gly-Pro-His-Arg-Ser-Thr-Pro-Glu-Ser-Arg-Ala-Ala-Val-OH Ref.: Kirschenbaum, F., et al. 2001. J. Biol. Chem. 276, 7366. |