H-KEAPPAPPQSpP-NH2
L803 White lyophilized solid. Supplied as a trifluoroacetate salt. HYGROSCOPIC. PACKAGED UNDER INERT GAS. A phosphorylated peptide that acts as a substrate-specific, competitive inhibitor of GSK-3b (IC50 = 150 µM). At 200 µM, weakly inhibits the activities of Cdc2, Casein Kinase II, MAPK, PKA, PKB, and PKCd. Purity: ≥95% by HPLC. H-Lys-Glu-Ala-Pro-Pro-Ala-Pro-Pro-Gln-Ser(PO3H)-Pro-NH2 Ref.: Plotkin, B., et al. 2003. J. Pharmacol. Exp. Ther. 305, 974.
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