N-[(2R)-2-(Carboxymethyl)-4-methylpentanoyl]-L-tryptophan-(S)-methyl-benzylamide Off-white solid. A potent broad-range inhibitor of matrix metalloproteinases (MMPs). Inhibits MMPs in vitro (Ki = 0.2 nM for MMP-1; Ki = 500 nM for MMP-2; Ki = 20 µM for MMP-3; Ki = 100 nM for MMP-8; and Ki = 100 nM for MMP-9). Also reduces the inflammatory and the hyperproliferative responses that occur following topical phorbol ester application. Purity: ≥95% by HPLC. CAS 170905-75-6. Ref.: Sato, N., et al. 2003. J. Natl. Cancer Inst. 95, 327. Holleran, W.M., et al. 1997. Arch. Dermatol. Res. 289, 138. | 
