gA White to off-white solid. Naturally-occurring ion channel-forming pentadecapeptide. The association of two gA peptides causes the formation of a monovalent cation-selective ion channel. Causes K+/H+ exchange in mitochondria in a non-voltage dependent manner. Causes red blood cell lysis at 0.5-1.0 µg/ml. Purity: ≥95% by HPLC. Contaminants: gB and gC isomers: <1% by HPLC. RTECS MD8230000, CAS 11029-61-1. HCO-Val-Gly-Ala-D-Leu-Ala-D-Val-Val-D-Val-Trp-D-Leu-Trp-D-Leu-Trp-D-Leu-Trp-NHCH2CH2OH Merck Index: 14, 4532
Ref.: Quigley, E.P., et al. 2000. J. Membr. Biol. 174, 207. Koeppe, R.E., et al. 1995. Biochemistry 34, 9299. Ketchem, R.R., et al. 1993. Science 261, 1457. Stankovic, C.J., et al. 1990. Anal. Biochem. 184, 100.
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