Z-AAD-CMK Off-white solid. PROTECT FROM MOISTURE. A weak inhibitor of the human and murine granzyme B. Also inhibits the apoptosis-related DNA fragmentation in lymphocytes by fragmentin 2, a rat lymphocyte granule protease homologous to granzyme B (ID50 = 300 nM). Purity: ≥95% by HPLC. Z-Ala-Ala-Asp-CH2Cl Ref.: Gong, B., et al. 1999. Cell Growth Different. 10, 491. Shi, L., et al. 1992. J. Exp. Med. 176, 1521. Odake, S., et al. 1991. Biochemistry 30, 2217. |
