Ac-IETD-CHO
Caspase-8 Inhibitor I White lyophilized solid. A potent, reversible inhibitor of granzyme B and caspase-8 (Ki = 1 nM). Also inhibits caspase-1 (<6 nM), caspase-6 (5.6 nM), and caspase-10 (27 nM). Purity: ≥95% by HPLC. Ac-Ile-Glu-Thr-Asp-CHO Ref.: Gao, C.F., et al. 2001. Exp. Cell. Res. 265, 145. Garcia-Calvo, M., et al. 1998. J. Biol. Chem. 273, 32608. Han, Z., et al. 1997. J. Biol. Chem. 272, 13422. |
