Caspase-8 Substrate II
Z-IETD-AFC White lyophilized solid. PROTECT FROM LIGHT. A fluorogenic substrate for the detection of granzyme B and caspase-8 activity. Reaction can be monitored visually or quantitatively by a blue to green shift in fluorescence upon cleavage of the AFC fluorophore. Purity: ≥97% by HPLC. Excitation max.: ~400 nm, Emission max.: ~505 nm Z-Ile-Glu-Thr-Asp-AFC Ref.: Karahashi, H., and Amano, F. 2000. Biol. Pharm. Bull. 23, 140. | 
