2,2′,3,3′,4,4′-Hexahydroxy-1,1′-biphenyl-6,6′-dimethanol Dimethyl Ether

Orange solid. PROTECT FROM LIGHT. PACKAGED UNDER INERT GAS. A cell-permeable protein kinase C (PKC) inhibitor that selectively inhibits PKC_a (IC₅₀ = 43 µM) and PKC_g (IC₅₀ = 50 µM) over PKC_d, b_I, and b_II isozymes in in vitro assays. Reported to induce apoptosis in rodent cerebellar granule neurons. Purity: ≥95% by TLC. CAS 154675-18-0.

Ref.: Mathur, A., and Vallano, M.L. 2000. Biochem. Pharmacol. 60, 809. Kashiwada, Y., et al. 1994. J. Med. Chem. 37, 195.