HEP, Na White solid. Prepared by depolymerization of heparin. Inhibits the IP3-activated Ca2+ release channel of the endoplasmic reticulum. Reported to activate the ryanodine receptor. Activity: Anti-Factor Xa activity: ≥70 units/mg dry weight. RTECS MI0850000, CAS 9041-08-1. Merck Index: 14, 4653 Ref.: Seuwen, K., and Boddeke, H.G. 1995. Br. J. Pharmacol. 114, 1613. Ehrlich, B.E., et al. 1994. Trends Pharmacol. Sci. 15,145. R: 22; S: 36 |