Oil dissolved in EtOH. 50 µg/ml in ethanol. An endogenous lipid mediator that increases intracellular Ca2+ release in human neutrophils in a biphasic manner. Activates the release of arachidonic acid and diacylglycerol. Modulates neurotransmission in the central nervous system through both its pre- and postsynaptic actions. Purity: ≥98% by TLC. Ref.: Reynaud, D., et al. 1999. FEBS Lett. 446, 236. Reynaud, D., et al. 1995. Biochem. Biophys. Res. Commun. 207, 191. Margalit, A., et al. 1993. Proc. Natl. Acad. Sci. USA 90, 2589. Piomelli, D. 1991. Am. J. Physiol. 260, R844. Kiel, D., et al. 1990. Adv. Prostaglandin Thromboxane Leuk. Res. 21A, 403. Pace-Asciak, C.R., et al. 1990. Biochem. Biophys. Res. Commun. 173, 949.
R: 11; S: 7-16 |
