HOE 33258
2-[2-(4-Hydroxyphenyl)-6-benzimidazoyl]-6-(1-methyl-4-piperazyl)-benzimidazole, 3HCl Yellow solid. PROTECT FROM LIGHT. Membrane-permeable, adenine-thymine-specific fluorescent stain. Useful for staining DNA, chromosomes, and nuclei. Increases the rate of channel-mediated Ca2+ efflux from junctional cytoplasmic reticulum vesicles. Can also be used to detect mycoplasma contamination in tissue culture. H 33258 and the related compound H 33342 (Cat. No. 382065) have been used in conjunction with RNA aptamers in the 5′ untranslated region (UTR) to control expression of transfected gene constructs. Purity: ≥98% by HPLC. Excitation max.: 346 nm, Emission max.: 460 nm RTECS SM1140500, CAS 23491-45-4. Ref.: Werstuck, G., and Green, M.R. 1998. Science 282, 296. Battaglio, M., et al. 1994. Biotech. Histochem. 69, 152. Elstein, K.H., and Zucker, R.M. 1994. Exp. Cell Res. 211, 322. Tarshis, M., et al. 1994. J. Immunol. Methods 168, 245. Beeler, T.J., and Gable, K. 1993. J. Membr. Biol. 135, 109. Oberhammer, F., et al. 1993. EMBO J. 12, 3679. Papadimitriou, E., and Lelkes, P.I. 1993. J. Immunol. Methods 162, 41. Jin, R., and Breslauer, K.J. 1988. Proc. Natl. Acad. Sci. USA 85, 8939. Cesarone, C.F., et al. 1979. Anal. Biochem. 100, 188. Latt, S.A., and Stetten, G. 1976. J. Histochem. Cytochem. 24, 24.
R: 36/37/38-40; S: 22-26-36 |
