HDAC Liquid. Native, enzymatically active, partially purified, histone deacetylase from rat liver. Useful in radioactive and in non-radioactive assays of histones. Can be useful to test the potency of HDAC inhibitors. Activity: ≥50 units/ml. One unit is the amount of enzyme required to deacylate 1 pmol Histone Deacetylase Substrate (Cat. No. 382155) per min at 37°C. Ref.: Hoffmann, K., et al. 2000. Pharmazie 55, 601. Hoffmann, K., et al. 1999. Nucleic Acids Res. 27, 2057. Brosch, G., et al. 1996. Biochemistry 35, 15907. |
