Liquid. In PBS. AVOID FREEZE/THAW CYCLES. Full-length, recombinant, human Hsp27 (amino acids 1-205) fused to a His·Tag® sequence at the N-terminus and expressed in S. frugiperda insect cells. Hsp27 acts as a molecular chaperone and has been shown to inhibit apoptosis and regulate cytoskeletal dynamics by acting as an actin-binding protein. Hsp27 has also been reported to have altered expression in some cancers. Purity: ≥90% by SDS-PAGE. Ref.: Garrido, C., et al. 2003. Cell Cycle 2, 579. Oesterreich, S., et al. 1993. Cancer Res. 53 4443. Thor, A., et al. 1991. J. Natl. Cancer Inst. 83, 170. |
