Ac-WVAD-AMC Lyophilized. PROTECT FROM LIGHT. PROTECT FROM MOISTURE. PACKAGED UNDER INERT GAS. A fluorogenic substrate for caspase-1 (kcat/Km = 2.41 x 105 M-1s-1) and caspase-4. Exhibits ~2 fold higher affinity towards caspase-1 than for caspase-4. Purity: ≥95% by HPLC. Excitation max.: 360–380 nm, Emission max.: 430–460 nm Ac-Trp-Val-Ala-Asp-AMC Ref.: Lee, D., et al. 1999. Bioorg. Med. Chem. Lett. 9, 1667. Rano, T.A., et al. 1997. Chem. Biol. 4, 149. |
