IL-1b Converting Enzyme (ICE) Substrate III
Ac-YVAD-AMC White solid. PROTECT FROM LIGHT. PROTECT FROM MOISTURE. Fluorogenic caspase-1 substrate (Km = 8 µM for human recombinant caspase-1). Also a substrate for caspase-4. Purity: ≥90% by HPLC. Excitation max.: 365–380 nm, Emission max.: 430–460 nm Ac-Tyr-Val-Ala-Asp-AMC Ref.: Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312. Walker, N.P.C., et al. 1994. Cell 78, 343. Thornberry, N.A., et al. 1992. Nature 356, 768. |
