NSC 698666 Yellow solid. PROTECT FROM LIGHT. PACKAGED UNDER INERT GAS. A potent cytostatic and cytotoxic indanone that blocks tubulin polymerization. Unlike other antimitotic agents, it induces apoptotic cell death in stationary-phase multidrug-resistant cancer cells at concentrations that do not impair the viability of normal non-proliferating cells. Purity: ≥97% by HPLC. Ref.: Leoni, L.M., et al. 2000. J. Natl. Cancer Res. Inst. 92, 217. |
