1-(p-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic Acid, 4-Methoxyphenyl Ester White solid. A cell-permeable 4-methoxyphenyl ester derivative of the non-steroidal anti-inflammatory drug (NSAID) Indomethacin (Cat. No. 405268) that acts as a potent and selective inhibitor of COX-2 (IC50 = 40 nM) compared to COX-1 (IC50 > 66 µM). Purity: ≥97% by HPLC. Ref.: Kalgutkar, A.S., et al. 2000. J. Med. Chem. 43, 2860. Kalgutkar, A.S., et al. 2000. Proc. Natl Acad. Sci. USA 97, 925. |
