D-Ins(1,4,5)P3, 3Li White solid. HYGROSCOPIC. Important metabolite that controls a variety of cellular functions such as proliferation, metabolism, and secretion. Enzymatic hydrolysis of the parent phospholipid produces Ins(1,4,5)P3, which is then released into the cytoplasm and functions as a second messenger for mobilization of Ca2+ from intracellular stores. Purity: ≥95% by HPLC. Ref.: Ferris, C.D., and Snyder, S.H. 1992. Annu. Rev. Physiol. 54, 469. Berridge, M.J. 1987. Annu. Rev. Biochem. 56, 159. Joseph, S.K., et al. 1984. J. Biol. Chem. 259, 3077. |
