rhIGF-II Lyophilized. Lyophilized from sterile-filtered acetic acid. Recombinant, human insulin-like growth factor-II expressed in E. coli. Its actions are similar to IGF-1 (Cat. No. 407240). Plays an important role in fetal development. Stimulates muscle and bone cell proliferation and differentiation. Biological activity: ED50 = 5-10 ng/ml. Purity: ≥97% by SDS-PAGE. Contaminants: Endotoxin: <1 EU/µg IGF-II. RTECS NM8906000, CAS 67763-97-7. Merck Index: 14, 4986
Ref.: Feldser, D., et al. 1999. Cancer Res. 59, 3915. Hill, P.A., et al. 1995. Endocrinology 136, 124. Nielson, F.C., et al. 1995. Nature 377, 358. LeRoith, D., and Roberts, C.R., Jr. 1993. Ann. N.Y. Acad. Sci. 692, 1. Lowe, W.L. 1991. In Insulin-Like Growth Factors: Molecular and Cellular Aspects (LeRoith, D., Ed.) CRC Press Inc., Boca Raton p. 49. Rotwein, P. 1991. Growth Factors 5, 3. |
